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Bayesian dose selection design for a binary outcome using restricted response adaptive randomization
BACKGROUND: In phase II trials, the most efficacious dose is usually not known. Moreover, given limited resources, it is difficult to robustly identify a dose while also testing for a signal of efficacy that would support a phase III trial. Recent designs have sought to be more efficient by explorin...
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| Publicado no: | Trials |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5591573/ https://ncbi.nlm.nih.gov/pubmed/28886745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-017-2004-6 |
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