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Two-stage Bayesian hierarchical modeling for blinded and unblinded safety monitoring in randomized clinical trials
BACKGROUND: Monitoring and reporting of drug safety during a clinical trial is essential to its success. More recent attention to drug safety has encouraged statistical methods development for monitoring and detecting potential safety signals. This paper investigates the potential impact of the proc...
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| Udgivet i: | BMC Med Res Methodol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7433072/ https://ncbi.nlm.nih.gov/pubmed/32807102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-020-01097-6 |
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