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Simulation Optimization for Bayesian Multi-Arm Multi-Stage Clinical Trial with Binary Endpoints
Multi-arm multi-stage designs, in which multiple active treatments are compared to a control and accumulated information from interim data are used to add or remove arms from the trial, may reduce development costs and shorten the drug development timeline. As such, this adaptive update is a natural...
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| Publicado no: | J Biopharm Stat |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7751063/ https://ncbi.nlm.nih.gov/pubmed/30763151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2019.1577682 |
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