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Tracing information flow from Erk to target gene induction reveals mechanisms of dynamic and combinatorial control

Cell signaling networks coordinate specific patterns of protein expression in response to external cues. Yet the logic by which signaling pathway activity determines the eventual abundance of target proteins is complex and poorly understood. Here, we describe an approach for simultaneously controlli...

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Publicado en:Mol Cell
Autores principales: Wilson, Maxwell Z., Ravindran, Pavithran T., Lim, Wendell A., Toettcher, Jared E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5591080/
https://ncbi.nlm.nih.gov/pubmed/28826673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.07.016
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