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Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module
The complex, interconnected architecture of cell-signaling networks makes it challenging to disentangle how cells process extracellular information to make decisions. We have developed an optogenetic approach to selectively activate isolated intracellular signaling nodes with light and use this meth...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925772/ https://ncbi.nlm.nih.gov/pubmed/24315106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.11.004 |
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