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Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module

The complex, interconnected architecture of cell-signaling networks makes it challenging to disentangle how cells process extracellular information to make decisions. We have developed an optogenetic approach to selectively activate isolated intracellular signaling nodes with light and use this meth...

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Bibliografiska uppgifter
Huvudupphovsmän: Toettcher, Jared E., Weiner, Orion D., Lim, Wendell A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925772/
https://ncbi.nlm.nih.gov/pubmed/24315106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.11.004
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