Application of a whole blood mycobacterial growth inhibition assay to study immunity against Mycobacterium tuberculosis in a high tuberculosis burden population

The determinants of immunological protection against Mycobacterium tuberculosis (M.tb) infection in humans are not known. Mycobacterial growth inhibition assays have potential utility as in vitro surrogates of in vivo immunological control of M.tb. We evaluated a whole blood growth inhibition assay...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Baguma, Richard, Penn-Nicholson, Adam, Smit, Erica, Erasmus, Mzwandile, Day, Jonathan, Makhethe, Lebohang, de Kock, Marwou, Hughes, E. Jane, van Rooyen, Michele, Pienaar, Bernadette, Stone, Lynnett, Hanekom, Willem, Brennan, Michael J., Wallis, Robert S., Hatherill, Mark, Scriba, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590973/
https://ncbi.nlm.nih.gov/pubmed/28886145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184563
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