HIV-1 infection is associated with depletion and functional impairment of Mycobacterium tuberculosis-specific CD4 T cells in individuals with latent tuberculosis infection()

Co-infection with HIV is the single greatest risk factor for reactivation of latent Mycobacterium tuberculosis infection (LTBI) and progression to active tuberculosis (TB) disease. HIV-associated dysregulation of adaptive immunity by depletion of CD4 T helper cells likely contributes to loss of immu...

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Publicado no:J Immunol
Main Authors: Day, Cheryl L., Abrahams, Deborah A., Harris, Levelle D., van Rooyen, Michele, Stone, Lynnett, de Kock, Marwou, Hanekom, Willem A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624214/
https://ncbi.nlm.nih.gov/pubmed/28760884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700558
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