Application of a whole blood mycobacterial growth inhibition assay to study immunity against Mycobacterium tuberculosis in a high tuberculosis burden population

The determinants of immunological protection against Mycobacterium tuberculosis (M.tb) infection in humans are not known. Mycobacterial growth inhibition assays have potential utility as in vitro surrogates of in vivo immunological control of M.tb. We evaluated a whole blood growth inhibition assay...

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Veröffentlicht in:PLoS One
Hauptverfasser: Baguma, Richard, Penn-Nicholson, Adam, Smit, Erica, Erasmus, Mzwandile, Day, Jonathan, Makhethe, Lebohang, de Kock, Marwou, Hughes, E. Jane, van Rooyen, Michele, Pienaar, Bernadette, Stone, Lynnett, Hanekom, Willem, Brennan, Michael J., Wallis, Robert S., Hatherill, Mark, Scriba, Thomas J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590973/
https://ncbi.nlm.nih.gov/pubmed/28886145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184563
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