Application of a whole blood mycobacterial growth inhibition assay to study immunity against Mycobacterium tuberculosis in a high tuberculosis burden population

The determinants of immunological protection against Mycobacterium tuberculosis (M.tb) infection in humans are not known. Mycobacterial growth inhibition assays have potential utility as in vitro surrogates of in vivo immunological control of M.tb. We evaluated a whole blood growth inhibition assay...

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Udgivet i:PLoS One
Main Authors: Baguma, Richard, Penn-Nicholson, Adam, Smit, Erica, Erasmus, Mzwandile, Day, Jonathan, Makhethe, Lebohang, de Kock, Marwou, Hughes, E. Jane, van Rooyen, Michele, Pienaar, Bernadette, Stone, Lynnett, Hanekom, Willem, Brennan, Michael J., Wallis, Robert S., Hatherill, Mark, Scriba, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590973/
https://ncbi.nlm.nih.gov/pubmed/28886145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184563
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