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Challenges and Opportunities in Targeting the CD28/CTLA-4 Pathway in Transplantation and Autoimmunity
INTRODUCTION: T cell activation is a complex process that requires multiple cell signaling pathways, including a primary recognition signal and additional costimulatory signals. One of the best-characterized costimulatory pathways includes the Ig superfamily members CD28 and CTLA-4 and their ligands...
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| Publicado en: | Expert Opin Biol Ther |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5590720/ https://ncbi.nlm.nih.gov/pubmed/28525959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14712598.2017.1333595 |
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