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Synthesis of bioactive and stabilized cyclic peptides by macrocyclization using C(sp(3))–H activation

Cyclic peptides have attracted increasing attention in recent years due to their ability to inhibit protein–protein interactions. Current strategies to prepare cyclic peptides often rely on functional amino acid side chains or the incorporation of unnatural amino acids, thus limiting their structura...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Tang, Jian, He, Yadong, Chen, Hongfei, Sheng, Wangjian, Wang, Huan
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590095/
https://ncbi.nlm.nih.gov/pubmed/28936334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc05530c
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