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Methodologies for Backbone Macrocyclic Peptide Synthesis Compatible With Screening Technologies
Backbone macrocyclic structures are often found in diverse bioactive peptides and contribute to greater conformational rigidity, peptidase resistance, and potential membrane permeability compared to their linear counterparts. Therefore, such peptide scaffolds are an attractive platform for drug-disc...
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| Udgivet i: | Front Chem |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7314982/ https://ncbi.nlm.nih.gov/pubmed/32626683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00447 |
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