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Synthesis of bioactive and stabilized cyclic peptides by macrocyclization using C(sp(3))–H activation

Cyclic peptides have attracted increasing attention in recent years due to their ability to inhibit protein–protein interactions. Current strategies to prepare cyclic peptides often rely on functional amino acid side chains or the incorporation of unnatural amino acids, thus limiting their structura...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Tang, Jian, He, Yadong, Chen, Hongfei, Sheng, Wangjian, Wang, Huan
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590095/
https://ncbi.nlm.nih.gov/pubmed/28936334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc05530c
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