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KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination
Maintenance of muscle function requires assembly of contractile proteins into highly organized sarcomeres. Mutations in Kelch-like protein 41 (KLHL41) cause nemaline myopathy, a fatal muscle disorder associated with sarcomere disarray. We generated KLHL41 mutant mice, which display lethal disruption...
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| Publicado no: | eLife |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5589419/ https://ncbi.nlm.nih.gov/pubmed/28826497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26439 |
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