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Myocardin-related transcription factors are required for skeletal muscle development

Myocardin-related transcription factors (MRTFs) play a central role in the regulation of actin expression and cytoskeletal dynamics. Stimuli that promote actin polymerization allow for shuttling of MRTFs to the nucleus where they activate serum response factor (SRF), a regulator of actin and other c...

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Detalles Bibliográficos
Publicado en:Development
Main Authors: Cenik, Bercin K., Liu, Ning, Chen, Beibei, Bezprozvannaya, Svetlana, Olson, Eric N., Bassel-Duby, Rhonda
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Ltd 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004908/
https://ncbi.nlm.nih.gov/pubmed/27385017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.135855
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