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GSK1904529A, a potent IGF-IR inhibitor, reverses MRP1-mediated multidrug resistance
Overexpression of multidrug-resistant efflux transporters is one of the major causes of chemotherapy failure. MRP1, a 190 kDa efflux transporter, confers resistance to a wide of range of chemotherapeutic drugs. Here we study the cellular effects of GSK1904529A in reversing MRP1-mediated drug resista...
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| Publicado no: | J Cell Biochem |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5589182/ https://ncbi.nlm.nih.gov/pubmed/28266043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25975 |
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