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Assessment of GSK1904529A as a promising anti-osteosarcoma agent

The insulin growth factor-I receptor (IGF1R) signaling is a key mechanism for osteosarcoma (OS) cell proliferation. GSK1904529A is a novel small molecule IGF1R kinase inhibitor. Its activity against OS cells was tested. In both established OS cell lines (Saos-2 and MG-63) and primary human OS cells,...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fei, Hao-Dong, Yuan, Qi, Mao, Li, Chen, Feng-Li, Cui, Zhao-Hui, Tao, Sha, Ji, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564795/
https://ncbi.nlm.nih.gov/pubmed/28572530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17911
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