Imatinib and Nilotinib Reverse Multidrug Resistance in Cancer Cells by Inhibiting the Efflux Activity of the MRP7 (ABCC10)

BACKGROUND: One of the major mechanisms that could produce resistance to antineoplastic drugs in cancer cells is the ATP binding cassette (ABC) transporters. The ABC transporters can significantly decrease the intracellular concentration of antineoplastic drugs by increasing their efflux, thereby lo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shen, Tong, Kuang, Ye-Hong, Ashby, Charles R., Lei, Yu, Chen, Angel, Zhou, Ying, Chen, Xiang, Tiwari, Amit K., Hopper-Borge, Elizabeth, Ouyang, Jiangyong, Chen, Zhe-Sheng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2009
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759525/
https://ncbi.nlm.nih.gov/pubmed/19841739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007520
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