Imatinib and Nilotinib Reverse Multidrug Resistance in Cancer Cells by Inhibiting the Efflux Activity of the MRP7 (ABCC10)

BACKGROUND: One of the major mechanisms that could produce resistance to antineoplastic drugs in cancer cells is the ATP binding cassette (ABC) transporters. The ABC transporters can significantly decrease the intracellular concentration of antineoplastic drugs by increasing their efflux, thereby lo...

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Hlavní autoři: Shen, Tong, Kuang, Ye-Hong, Ashby, Charles R., Lei, Yu, Chen, Angel, Zhou, Ying, Chen, Xiang, Tiwari, Amit K., Hopper-Borge, Elizabeth, Ouyang, Jiangyong, Chen, Zhe-Sheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759525/
https://ncbi.nlm.nih.gov/pubmed/19841739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007520
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