Cardiometabolic effects of a novel SIRT1 activator, SRT2104, in people with type 2 diabetes mellitus

BACKGROUND: The cardiometabolic effects of SRT2104, a novel SIRT1 activator, were investigated in people with type 2 diabetes mellitus (T2DM). METHODS: Fifteen adults with T2DM underwent a randomised, double-blind, placebo-controlled cross-over trial and received 28 days of oral SRT2104 (2.0 g/day)...

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Detalhes bibliográficos
Publicado no:Open Heart
Main Authors: Noh, Radzi M, Venkatasubramanian, Sowmya, Daga, Shruti, Langrish, Jeremy, Mills, Nicholas L, Lang, Ninian N, Hoffmann, Ethan, Waterhouse, Brian, Newby, David E, Frier, Brian M
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Basic and Translational Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588958/
https://ncbi.nlm.nih.gov/pubmed/28912956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/openhrt-2017-000647
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