Cardiovascular Effects of a Novel SIRT1 Activator, SRT2104, in Otherwise Healthy Cigarette Smokers

BACKGROUND: We examined the effect of the oral SIRT1 activator SRT2104 on cardiovascular function in otherwise healthy cigarette smokers. METHODS AND RESULTS: Twenty‐four otherwise healthy cigarette smokers participated in a randomized double‐blind, placebo‐controlled crossover trial and received 28...

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Autors principals: Venkatasubramanian, Sowmya, Noh, Radzi Mohd, Daga, Shruti, Langrish, Jeremy P., Joshi, Nikhil V., Mills, Nicholas L., Hoffmann, Ethan, Jacobson, Eric W., Vlasuk, George P., Waterhouse, Brian R., Lang, Ninian N., Newby, David E.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2013
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698759/
https://ncbi.nlm.nih.gov/pubmed/23770971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000042
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