UPF1 helicase promotes TSN-mediated miRNA decay

While microRNAs (miRNAs) regulate the vast majority of protein-encoding transcripts, little is known about how miRNAs themselves are degraded. We recently described Tudor-staphylococcal/micrococcal-like nuclease (TSN)-mediated miRNA decay (TumiD) as a cellular pathway in which the nuclease TSN promo...

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Bibliografske podrobnosti
izdano v:Genes Dev
Main Authors: Elbarbary, Reyad A., Miyoshi, Keita, Hedaya, Omar, Myers, Jason R., Maquat, Lynne E.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2017
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588929/
https://ncbi.nlm.nih.gov/pubmed/28827400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.303537.117
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