Abro1 maintains genome stability and limits replication stress by protecting replication fork stability

Protection of the stalled replication fork is crucial for responding to replication stress and minimizing its impact on chromosome instability, thus preventing diseases, including cancer. We found a new component, Abro1, in the protection of stalled replication fork integrity. Abro1 deficiency resul...

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Опубликовано в: :Genes Dev
Главные авторы: Xu, Shengfeng, Wu, Xiao, Wu, Ling, Castillo, Andy, Liu, Jianxin, Atkinson, Erin, Paul, Atanu, Su, Dan, Schlacher, Katharina, Komatsu, Yoshihiro, You, M. James, Wang, Bin
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2017
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588928/
https://ncbi.nlm.nih.gov/pubmed/28860160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.299172.117
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