Abro1 maintains genome stability and limits replication stress by protecting replication fork stability

Protection of the stalled replication fork is crucial for responding to replication stress and minimizing its impact on chromosome instability, thus preventing diseases, including cancer. We found a new component, Abro1, in the protection of stalled replication fork integrity. Abro1 deficiency resul...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Dev
Prif Awduron: Xu, Shengfeng, Wu, Xiao, Wu, Ling, Castillo, Andy, Liu, Jianxin, Atkinson, Erin, Paul, Atanu, Su, Dan, Schlacher, Katharina, Komatsu, Yoshihiro, You, M. James, Wang, Bin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2017
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5588928/
https://ncbi.nlm.nih.gov/pubmed/28860160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.299172.117
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