Determination of optimal sites of antisense oligonucleotide cleavage within TNFα mRNA

Antisense oligonucleotides provide a powerful tool in order to determine the consequences of the reduced expression of a selected target gene and may include target validation and therapeutic applications. Methods of predicting optimum antisense sites are not always effective. We have compared the e...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Lloyd, B. H., Giles, R. V., Spiller, D. G., Grzybowski, J., Tidd, D. M., Sibson, D. R.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 2001
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55886/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11522838/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.17.3664
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