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Determination of optimal sites of antisense oligonucleotide cleavage within TNFα mRNA

Antisense oligonucleotides provide a powerful tool in order to determine the consequences of the reduced expression of a selected target gene and may include target validation and therapeutic applications. Methods of predicting optimum antisense sites are not always effective. We have compared the e...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Lloyd, B. H., Giles, R. V., Spiller, D. G., Grzybowski, J., Tidd, D. M., Sibson, D. R.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55886/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11522838/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.17.3664
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