Chd2 regulates chromatin for proper gene expression toward differentiation in mouse embryonic stem cells

Chromatin reorganization is necessary for pluripotent stem cells, including embryonic stem cells (ESCs), to acquire lineage potential. However, it remains unclear how ESCs maintain their characteristic chromatin state for appropriate gene expression upon differentiation. Here, we demonstrate that ch...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Semba, Yuichiro, Harada, Akihito, Maehara, Kazumitsu, Oki, Shinya, Meno, Chikara, Ueda, Jun, Yamagata, Kazuo, Suzuki, Atsushi, Onimaru, Mitsuho, Nogami, Jumpei, Okada, Seiji, Akashi, Koichi, Ohkawa, Yasuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587750/
https://ncbi.nlm.nih.gov/pubmed/28549158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx475
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