Biochemical analysis of nucleosome targeting by Tn5 transposase

Tn5 transposase is a bacterial enzyme that integrates a DNA fragment into genomic DNA, and is used as a tool for detecting nucleosome-free regions of genomic DNA in eukaryotes. However, in chromatin, the DNA targeting by Tn5 transposase has remained unclear. In the present study, we reconstituted we...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Shoko Sato, Yasuhiro Arimura, Tomoya Kujirai, Akihito Harada, Kazumitsu Maehara, Jumpei Nogami, Yasuyuki Ohkawa, Hitoshi Kurumizaka
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2019-08-01
Colecção:Open Biology
Assuntos:
tn5 transposase
chromatin
nucleosome
linker dna
nucleosome-free region
Acesso em linha:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.190116
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados