Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA

DNA methylation occurs on CpG sites and is important to form pericentric heterochromatin domains. The satellite 2 sequence, containing seven CpG sites, is located in the pericentric region of human chromosome 1 and is highly methylated in normal cells. In contrast, the satellite 2 region is reported...

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Bibliografiske detaljer
Udgivet i:Open Biol
Main Authors: Osakabe, Akihisa, Adachi, Fumiya, Arimura, Yasuhiro, Maehara, Kazumitsu, Ohkawa, Yasuyuki, Kurumizaka, Hitoshi
Format: Artigo
Sprog:Inglês
Udgivet: The Royal Society 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632512/
https://ncbi.nlm.nih.gov/pubmed/26446621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150128
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