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Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA

DNA methylation occurs on CpG sites and is important to form pericentric heterochromatin domains. The satellite 2 sequence, containing seven CpG sites, is located in the pericentric region of human chromosome 1 and is highly methylated in normal cells. In contrast, the satellite 2 region is reported...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Osakabe, Akihisa, Adachi, Fumiya, Arimura, Yasuhiro, Maehara, Kazumitsu, Ohkawa, Yasuyuki, Kurumizaka, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632512/
https://ncbi.nlm.nih.gov/pubmed/26446621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.150128
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