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Biochemical analysis of nucleosome targeting by Tn5 transposase
Tn5 transposase is a bacterial enzyme that integrates a DNA fragment into genomic DNA, and is used as a tool for detecting nucleosome-free regions of genomic DNA in eukaryotes. However, in chromatin, the DNA targeting by Tn5 transposase has remained unclear. In the present study, we reconstituted we...
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| Udgivet i: | Open Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6731594/ https://ncbi.nlm.nih.gov/pubmed/31409230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.190116 |
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