Chd2 regulates chromatin for proper gene expression toward differentiation in mouse embryonic stem cells

Chromatin reorganization is necessary for pluripotent stem cells, including embryonic stem cells (ESCs), to acquire lineage potential. However, it remains unclear how ESCs maintain their characteristic chromatin state for appropriate gene expression upon differentiation. Here, we demonstrate that ch...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Semba, Yuichiro, Harada, Akihito, Maehara, Kazumitsu, Oki, Shinya, Meno, Chikara, Ueda, Jun, Yamagata, Kazuo, Suzuki, Atsushi, Onimaru, Mitsuho, Nogami, Jumpei, Okada, Seiji, Akashi, Koichi, Ohkawa, Yasuyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587750/
https://ncbi.nlm.nih.gov/pubmed/28549158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx475
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