Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke

Treatment of acute ischemic stroke with the thrombolytic tissue plasminogen activator (tPA) can significantly improve neurological outcomes; however, thrombolytic therapy is associated with an increased risk of intra-cerebral hemorrhage (ICH). Previously, we demonstrated that during stroke tPA actin...

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Pubblicato in:Acta Neuropathol
Autori principali: Su, Enming Joseph, Cao, Chunzhang, Fredriksson, Linda, Nilsson, Ingrid, Stefanitsch, Christina, Stevenson, Tamara K., Zhao, Juanjuan, Ragsdale, Margret, Sun, Yu-Yo, Yepes, Manuel, Kuan, Chia-Yi, Eriksson, Ulf, Strickland, Dudley K., Lawrence, Daniel A., Zhang, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2017
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Original Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587628/
https://ncbi.nlm.nih.gov/pubmed/28725968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-017-1749-z
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