Llwytho...

IL-2-induced expression of the amino acid transporters SLC1A5 and CD98 is a prerequisite for NKG2D-mediated activation of human NK cells

Priming of human NK cells with IL-2 is necessary to render them functionally competent upon NKG2D engagement. We examined the underlying mechanisms that control NKG2D responsiveness in NK cells and found that IL-2 up-regulates expression of the amino acid transporters solute carrier family 1 member...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Jensen, Helle, Potempa, Marc, Gotthardt, Dagmar, Lanier, Lewis L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587401/
https://ncbi.nlm.nih.gov/pubmed/28784848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700497
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