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Cytotoxicity of CD56(bright) NK Cells towards Autologous Activated CD4(+) T Cells Is Mediated through NKG2D, LFA-1 and TRAIL and Dampened via CD94/NKG2A

In mouse models of chronic inflammatory diseases, Natural Killer (NK) cells can play an immunoregulatory role by eliminating chronically activated leukocytes. Indirect evidence suggests that NK cells may also be immunoregulatory in humans. Two subsets of human NK cells can be phenotypically distingu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nielsen, Natasja, Ødum, Niels, Ursø, Birgitte, Lanier, Lewis L., Spee, Pieter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284517/
https://ncbi.nlm.nih.gov/pubmed/22384114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031959
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