TGF-β downregulates the activating receptor NKG2D on NK cells and CD8(+) T cells in glioma patients

The activating receptor NKG2D, expressed by natural killer (NK) cells and CD8(+) T cells, has a role in the specific killing of transformed cells. We examined NKG2D expression in patients with glioblastoma multiforme and found that NKG2D was downregulated on NK cells and CD8(+) T cells. Expression o...

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Autors principals: Crane, Courtney A., Han, Seunggu J., Barry, Jeffery J., Ahn, Brian J., Lanier, Lewis L., Parsa, Andrew T.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Rapid Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940557/
https://ncbi.nlm.nih.gov/pubmed/20150362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nop009
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