In silico modeling identifies CD45 as a regulator of IL-2 synergy in the NKG2D-mediated activation of immature human NK cells

Natural killer (NK) cells perform immunosurveillance of virally infected and transformed cells, and their activation depends on the balance between signaling by inhibitory and activating receptors. Cytokine receptor signaling can synergize with activating receptor signaling to induce NK cell activat...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Signal
Egile Nagusiak: Mukherjee, Sayak, Jensen, Helle, Stewart, William, Stewart, David, Ray, William C., Chen, Shih-Yu, Nolan, Garry P., Lanier, Lewis L., Das, Jayajit
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556952/
https://ncbi.nlm.nih.gov/pubmed/28655861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aai9062
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