Cargando...
Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization
The epithelial FGF9 subfamily specifically binds and activates the mesenchymal ‘c’ splice isoform of FGF receptor 1–3 to regulate organogenesis and tissue homeostasis. The unique N and C-termini of FGF9 subfamily ligands mediate a reversible homodimerization that occludes major receptor binding site...
Guardado en:
| Publicado en: | Structure |
|---|---|
| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5587394/ https://ncbi.nlm.nih.gov/pubmed/28757146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.06.016 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|