Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade

Previous data indicate that Tankyrase inhibitors exert anti-growth functions in many cancer cell lines due to their ability to inactivate the YAP protooncogene. In the present manuscript, we investigated the effect of Tankyrase inhibitors on the growth of hepatocellular carcinoma (HCC) cell lines an...

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Foilsithe in:PLoS One
Main Authors: Jia, Jiaoyuan, Qiao, Yu, Pilo, Maria G., Cigliano, Antonio, Liu, Xianqiong, Shao, Zixuan, Calvisi, Diego F., Chen, Xin
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587291/
https://ncbi.nlm.nih.gov/pubmed/28877210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184068
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