Hippo Cascade Controls Lineage Commitment of Liver Tumors in Mice and Humans

Primary liver cancer consists mainly of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). A subset of human HCCs expresses a ICC-like gene signature and is classified as ICC-like HCC. The Hippo pathway is a critical regulator of normal and malignant liver development. However...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Zhang, Shanshan, Wang, Jingxiao, Wang, Haichuan, Fan, Lingling, Fan, Biao, Zeng, Billy, Tao, Junyan, Li, Xiaolei, Che, Li, Cigliano, Antonio, Ribback, Silvia, Dombrowski, Frank, Chen, Bin, Cong, Wenming, Wei, Lixin, Calvisi, Diego F., Chen, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866106/
https://ncbi.nlm.nih.gov/pubmed/29378174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.12.017
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