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Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology

Newly synthesized membrane proteins are targeted to the inner nuclear membrane (INM) by diffusion within the membrane system of the endoplasmic reticulum (ER), translocation through nuclear pore complexes (NPCs) and retention on nuclear partners. Using a visual in vitro assay we previously showed th...

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Pubblicato in:eLife
Autori principali: Pawar, Sumit, Ungricht, Rosemarie, Tiefenboeck, Peter, Leroux, Jean-Christophe, Kutay, Ulrike
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587084/
https://ncbi.nlm.nih.gov/pubmed/28826471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28202
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