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Diffusion and retention are major determinants of protein targeting to the inner nuclear membrane

Newly synthesized membrane proteins are constantly sorted from the endoplasmic reticulum (ER) to various membranous compartments. How proteins specifically enrich at the inner nuclear membrane (INM) is not well understood. We have established a visual in vitro assay to measure kinetics and investiga...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Ungricht, Rosemarie, Klann, Michael, Horvath, Peter, Kutay, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460150/
https://ncbi.nlm.nih.gov/pubmed/26056139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201409127
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