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Diffusion and retention are major determinants of protein targeting to the inner nuclear membrane

Newly synthesized membrane proteins are constantly sorted from the endoplasmic reticulum (ER) to various membranous compartments. How proteins specifically enrich at the inner nuclear membrane (INM) is not well understood. We have established a visual in vitro assay to measure kinetics and investiga...

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Vydáno v:J Cell Biol
Hlavní autoři: Ungricht, Rosemarie, Klann, Michael, Horvath, Peter, Kutay, Ulrike
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460150/
https://ncbi.nlm.nih.gov/pubmed/26056139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201409127
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