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Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology

Newly synthesized membrane proteins are targeted to the inner nuclear membrane (INM) by diffusion within the membrane system of the endoplasmic reticulum (ER), translocation through nuclear pore complexes (NPCs) and retention on nuclear partners. Using a visual in vitro assay we previously showed th...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Pawar, Sumit, Ungricht, Rosemarie, Tiefenboeck, Peter, Leroux, Jean-Christophe, Kutay, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587084/
https://ncbi.nlm.nih.gov/pubmed/28826471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28202
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