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Dissociation of membrane–chromatin contacts is required for proper chromosome segregation in mitosis

The nuclear envelope (NE) aids in organizing the interphase genome by tethering chromatin to the nuclear periphery. During mitotic entry, NE–chromatin contacts are broken. Here, we report on the consequences of impaired NE removal from chromatin for cell division of human cells. Using a membrane–chr...

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Bibliografiska uppgifter
I publikationen:Mol Biol Cell
Huvudupphovsmän: Champion, Lysie, Pawar, Sumit, Luithle, Naemi, Ungricht, Rosemarie, Kutay, Ulrike
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594442/
https://ncbi.nlm.nih.gov/pubmed/30586323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-10-0609
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