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Dissociation of membrane–chromatin contacts is required for proper chromosome segregation in mitosis

The nuclear envelope (NE) aids in organizing the interphase genome by tethering chromatin to the nuclear periphery. During mitotic entry, NE–chromatin contacts are broken. Here, we report on the consequences of impaired NE removal from chromatin for cell division of human cells. Using a membrane–chr...

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Dades bibliogràfiques
Publicat a:Mol Biol Cell
Autors principals: Champion, Lysie, Pawar, Sumit, Luithle, Naemi, Ungricht, Rosemarie, Kutay, Ulrike
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594442/
https://ncbi.nlm.nih.gov/pubmed/30586323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-10-0609
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