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Dissociation of membrane–chromatin contacts is required for proper chromosome segregation in mitosis

The nuclear envelope (NE) aids in organizing the interphase genome by tethering chromatin to the nuclear periphery. During mitotic entry, NE–chromatin contacts are broken. Here, we report on the consequences of impaired NE removal from chromatin for cell division of human cells. Using a membrane–chr...

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Bibliografske podrobnosti
izdano v:Mol Biol Cell
Main Authors: Champion, Lysie, Pawar, Sumit, Luithle, Naemi, Ungricht, Rosemarie, Kutay, Ulrike
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594442/
https://ncbi.nlm.nih.gov/pubmed/30586323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-10-0609
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