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Nuclear envelope expansion is crucial for proper chromosomal segregation during a closed mitosis
Here, we screened a 10,371 library of diverse molecules using a drug-sensitive fission yeast strain to identify compounds which cause defects in chromosome segregation during mitosis. We identified a phosphorium-ylide-based compound Cutin-1 which inhibits nuclear envelope expansion and nuclear elong...
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| Опубликовано в: : | J Cell Sci |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Company of Biologists Ltd
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813296/ https://ncbi.nlm.nih.gov/pubmed/26869222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.181560 |
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