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Nuclear envelope expansion is crucial for proper chromosomal segregation during a closed mitosis

Here, we screened a 10,371 library of diverse molecules using a drug-sensitive fission yeast strain to identify compounds which cause defects in chromosome segregation during mitosis. We identified a phosphorium-ylide-based compound Cutin-1 which inhibits nuclear envelope expansion and nuclear elong...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Takemoto, Ai, Kawashima, Shigehiro A., Li, Juan-Juan, Jeffery, Linda, Yamatsugu, Kenzo, Elemento, Olivier, Nurse, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813296/
https://ncbi.nlm.nih.gov/pubmed/26869222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.181560
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