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Nuclear envelope expansion is crucial for proper chromosomal segregation during a closed mitosis
Here, we screened a 10,371 library of diverse molecules using a drug-sensitive fission yeast strain to identify compounds which cause defects in chromosome segregation during mitosis. We identified a phosphorium-ylide-based compound Cutin-1 which inhibits nuclear envelope expansion and nuclear elong...
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| Publicat a: | J Cell Sci |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Company of Biologists Ltd
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4813296/ https://ncbi.nlm.nih.gov/pubmed/26869222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.181560 |
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