p53 and Mdm2 act synergistically to maintain cardiac homeostasis and mediate cardiomyocyte cell cycle arrest through a network of microRNAs

Defining the roadblocks responsible for cell cycle arrest in adult cardiomyocytes lies at the core of developing cardiac regenerative therapies. p53 and Mdm2 are crucial mediators of cell cycle arrest in proliferative cell types, however, little is known about their function in regulating homeostasi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Cycle
Egile Nagusiak: Stanley-Hasnain, Shanna, Hauck, Ludger, Grothe, Daniela, Aschar-Sobbi, Roozbeh, Beca, Sanja, Butany, Jagdish, Backx, Peter H., Mak, Tak W., Billia, Filio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2017
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587026/
https://ncbi.nlm.nih.gov/pubmed/28745540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1346758
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