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Arsenite Binds to the RING Finger Domain of FANCL E3 Ubiquitin Ligase and Inhibits DNA Interstrand Crosslink Repair

Human exposure to arsenic in drinking water is known to be associated with the development of bladder, lung, kidney, and skin cancers. The molecular mechanisms underlying the carcinogenic effects of arsenic species remain incompletely understood. DNA interstrand cross-links (ICLs) are among the most...

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Detaylı Bibliyografya
Yayımlandı:ACS Chem Biol
Asıl Yazarlar: Jiang, Ji, Bellani, Marina, Li, Lin, Wang, Pengcheng, Seidman, Michael M., Wang, Yinsheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586398/
https://ncbi.nlm.nih.gov/pubmed/28535027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b01135
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