Wird geladen...

Arsenite Binds to the RING Finger Domain of FANCL E3 Ubiquitin Ligase and Inhibits DNA Interstrand Crosslink Repair

Human exposure to arsenic in drinking water is known to be associated with the development of bladder, lung, kidney, and skin cancers. The molecular mechanisms underlying the carcinogenic effects of arsenic species remain incompletely understood. DNA interstrand cross-links (ICLs) are among the most...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:ACS Chem Biol
Hauptverfasser: Jiang, Ji, Bellani, Marina, Li, Lin, Wang, Pengcheng, Seidman, Michael M., Wang, Yinsheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586398/
https://ncbi.nlm.nih.gov/pubmed/28535027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b01135
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!