The DNA Translocase FANCM/MHF Promotes Replication Traverse of DNA Interstrand Crosslinks

The replicative machinery encounters many impediments, some of which can be overcome by lesion bypass or replication restart pathways, leaving repair for a later time. However, interstrand crosslinks (ICLs), which preclude DNA unwinding, are considered absolute blocks to replication. Current models...

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Autores principales: Huang, Jing, Liu, Shuo, Bellani, Marina, Thazhathveetil, Arun Kalliat, Ling, Chen, de Winter, Johan P., Wang, Yinsheng, Wang, Weidong, Seidman, Michael M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880019/
https://ncbi.nlm.nih.gov/pubmed/24207054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.09.021
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