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The DNA Translocase FANCM/MHF Promotes Replication Traverse of DNA Interstrand Crosslinks
The replicative machinery encounters many impediments, some of which can be overcome by lesion bypass or replication restart pathways, leaving repair for a later time. However, interstrand crosslinks (ICLs), which preclude DNA unwinding, are considered absolute blocks to replication. Current models...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3880019/ https://ncbi.nlm.nih.gov/pubmed/24207054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.09.021 |
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