Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates Fibrosis

BACKGROUND: Acute kidney injury (AKI) is a major risk factor for the development of chronic kidney disease. Nuclear factor‐κB is a nuclear transcription factor activated post‐ischemia, responsible for the transcription of proinflammatory proteins. The role of nuclear factor‐κB in the renal fibrosis...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Johnson, Florence L., Patel, Nimesh S. A., Purvis, Gareth S. D., Chiazza, Fausto, Chen, Jianmin, Sordi, Regina, Hache, Guillaume, Merezhko, Viktoria V., Collino, Massimo, Yaqoob, Muhammed M., Thiemermann, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5586267/
https://ncbi.nlm.nih.gov/pubmed/28673900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.116.005092
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